Astrological research on heart disease, while not a replacement for modern medicine, can offer a complementary perspective by examining potential planetary influences and individual predispositions. This research could potentially aid in risk assessment, diagnosis and even treatment planning by considering astrological factors.

In medical astrology study of any disease starts with checking affliction of ascendent and ascendent lord as it favours any disease to develop. Study of heart disease is based on studying affliction of important planets such as Sun being main significator of heart, Moon as secondary significator of heart, Role of malefic planets like Mars,Saturn, Rahu and Ketu. Important houses such as fourth and fifth houses and their lords connection with evil houses and their lords [6/8/12 houses and their lords]. Apart from this some constellations also play important role. For study of event of heart attack, transit along with dasha periods are crucial.

A study of heart disease in 100 natives applying 14 rules is carried out, aggregate percentage of application of all the 14 rules is about 89%, while percentage of application of individual rule in all the 100 natives ranged from 70 to 100%.